Tiny silver nanoparticles kills bacteria efficiently, including strains that cause acne. It’s not Magic, It’s Science!

According to this publication the possible mechanisms of silver nanoparticles (AgNPs) action are:
1. Better contact with the microorganism – nanometer scale silver provides an extremely large surface area for contact with bacteria. The nanoparticles get attached to the cell membrane and also penetrate inside the bacteria;

2. Bacterial membranes contain sulfur-containing proteins and AgNPs, like Ag+, can interact with them as well as with phosphorus-containing compounds like DNA, perhaps to inhibit the function;

3. Silver (nanoparticles or Ag+) can attack the respiratory chain in bacterial mitochondria and lead to cell death;

4. AgNPs can have a sustained release of Ag+ once inside the bacterial cells (in an environment with lower pH), which may create free radicals and induce oxidative stress, thus further enhancing their bactericidal activity (Fig. 2). Furthermore, a recent study showed that yeast and E. coli were inhibited at a low concentration of AgNPs, study of mechanisms revealed that free radicals and oxidative stress were responsible for the antibacterial activities.

Fig. 2 A schematic drawing showing the various mechanisms of antibacterial activities exerted by silver nanoparticles.

 

Our team developed unique technologies for obtaining silver nanoparticles and discovered a way of their stabilization in such products as soap and foam.

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The Evolut Team

Evolut is an international group of scientists and physicians with a research center and head office in Togliatti, Russia.